Driving by the boring life they have in the small town of South Park, Colorado, and their love for adventures, four young boys, make dangerous adventures, as their participation on the dangerous attempt of photographic meme, the thing that brings terrible for them as usual.
If "Reverse Cowgirl" wasn't the most laugh-out-loud funny the show's done in the recent past, it... certainly had sharp points to make about government encroachment in the lives of Americans.
The brilliantly goofy sequence sends up the style of Dr. Seuss, but it also points up some parallels between him and Trey and Matt that I would not otherwise have thought of.